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The Historical Subject Files Collection documents Columbia University history and related topics from 1754 to the present. The collection includes articles, booklets, clippings, correspondence, memoranda, non-photographic images, notes, pamphlets, posters, press releases, programs and reports.

This collection contains correspondence, research files, speeches, writings and other records related to Katharine F. Lenroot, a child welfare leader and the third Chief of the United States Children's Bureau (1934-1951). Lenroot served the Children's Bureau from its earliest years, and contributed significantly to the bureau's development during the New Deal and to the establishment of United Nations International Children's Emergency Fund after World War II. Most of the Papers relate to her professional career, and materials dating from her Washington years comprise the largest part of this collection. After her retirement Lenroot continued to devote herself to issues of child welfare at the state, national and international level

Eric R. Kandel is a neuroscientist and the recipient of the 2000 Nobel Prize in Physiology or Medicine for "discoveries concerning signal transduction in the nervous system." The papers include awards files, clippings, correspondence, grant files, lectures, photographs, publications, reprints, syllabi, videotapes, and dissertations written by Kandel's students.