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The collection consiste of correspondence, memoranda, reports, bulletins, clippings, photographs, awards, and printed material. The files, arranged by genre and topic and reflect her philanthropic and legislative work in the areas of health, specifically cancer, heart disease, and mental health. Her civic and legislative work is covered in detail, as well as her private interests and activities.

Correspondence, manuscripts, typescripts, research files, documents, printed materials, photographs, and memorabilia of Mr and Mrs Hough. Correspondence includes both personal and business letters, dealing with wildlife conservation, civic interests, and birding. There is some correspondence of George A. Hough, Sr., father of H.B. Hough, who was editor of the New Bedford MA Standard. Most of the correspondence is arranged alphabetically, by personal name or subject, out-going and in-coming filed together. Henry and Elizabeth Hough's correspondence, for which there are no in-coming or related letters, are filed chronologically. Cataloged correspondents include Calvin Coolidge, Max Eastman, Helen Keller, John F. Kennedy, Emily Post, and James Reston.